• While resistance to imatinib is

  2019-04-26

  

  While resistance to imatinib is rare in patients treated in CML-CP, resistance does eventually develop in the majority of patients treated in the advanced phases. In a high proportion of patients who develop secondary resistance after initial responses, point mutations in the BCR-ABL kinase domain h

• WHO estimates that of people with tuberculosis are untreated

  2019-04-26

  

  WHO estimates that 30–50% of people with tuberculosis are untreated, in part because of underdiagnosis. Patients with undiagnosed (or diagnosed and untreated) tuberculosis are most likely to transmit infection, so strategies to reduce disease burden should focus on improving the pathway to care for

• In the American College of Chest Physicians

  2019-04-26

  

  In 2013, the American College of Chest Physicians provided a guideline to the preoperative physiological assessment of patients being considered for surgical resection of lung cancer. It has been recommended that patients must be assessed by a multidisciplinary team before operation, regardless of a

• br Conclusions br Acknowledgements This work was supported b

  2019-04-25

  

  Conclusions Acknowledgements This work was supported by Bloodwise, the International Myeloma Foundation and a Marie Curie Career Integration Grant from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement n° [294160]. The osteoblast in normal bone physiology

• Ante la necesidad de unas

  2019-04-25

  

  Ante la necesidad de unas reglas o códigos sildenafil mesylate partir de los cuales evaluar la producción de los decadentistas, el autor del artículo se lamenta de su inexistencia: “¿Dónde está el código de los decadentistas? No le tienen porque en vez de reglas lo que ellos practican es la violació

• Fujimori fei eleito presidente neste contexto cr

  2019-04-25

  

  Fujimori fei eleito presidente neste contexto crítico com uma plataforma que parecia capturar, ao mesmo tempo, o rechaço popular à política criolla personificada em Vargas Llosa, e uma desconfiança em relação às ambiguidades da esquerda, que oscilava entre um passado radical como Sendero ou um futur

• Phos-tag Biotin BTL-105 A preserva o da ideia de fam lia tra

  2019-04-25

  

  A preservação da ideia de família tradicional tornou-se uma das principais demandas desses representantes. Neste sentido, o Projeto de Lei n° 6583 de 2011, conhecido como Estatuto da Família, almeja o reconhecimento (pelo Estado) da família como uma entidade formada apenas por um homem, uma mulher e

• The overall MSTS score in our study was The

  2019-04-25

  

  The overall MSTS score in our study was 97.3%. The MSTS score after curettage treatment was 99%, better than that in previous studies, which ranged from 90% to 93%. Two cohort studies showed higher MSTS scores for patients who underwent intralesional curettage than those who underwent wide resection

• In this section we will

  2019-04-25

  

  In this section we will try and address many of the frequently asked questions around preventive and prophylactic measures for patients either starting or already established on bone-targeted therapy (Figs. 2 and 3). In view of the difficulties in treating ONJ, preventive strategies would seem to ma

• Introduction Metastasis to the bone is a common complication

  2019-04-25

  

  Introduction Metastasis to the bone is a common complication of breast, lung, prostate, gastrointestinal, haematological, melanoma, and other tumours [1–3]. In many patients with primary breast, prostate and lung primary tumours, bone metastases (BoM) are signs associated with the presence of disse

• br Conclusion br Limitations br Conflict

  2019-04-25

  

  Conclusion Limitations Conflict of interest Introduction The prevalence of daunorubicin failure prevalence is increasing throughout the world. The reasons for this pandemic include the aging populations of both industrialized and developing nations and a growing incidence of obesity, dia

• En el cuento el protagonista es

  2019-04-25

  

  En el cuento, el protagonista es sometido arecoline hydrobromide los abusos de la mercantilización del objeto artístico y de una distorsionada crítica de arte que buscan en él diversas explicaciones o justificaciones a su propia razón de ser a través de mecanismos legitimadores, enmarcados en el ent

• M s all del justificado resentimiento de

  2019-04-25

  

  Más allá del justificado resentimiento de los tamaulipecos, es el escritor Mauricio Magdaleno en su antología Escritores extranjeros en la Revolución (1979), quien ofrece el juicio más interesante sobre la novela, en su breve presentación del autor norteamericano. A diferencia de Gunn, para quien Ta

• Macrophages in bone metastasis main outstanding questions br

  2019-04-24

  

  Macrophages in bone metastasis – main outstanding questions: Conflict of interest statement Acknowledgements IV was supported by a generous grant from Weston Park Hospital Cancer Charity, Sheffield, UK. Introduction In recent years there has been increasing interest in the role of bone-ta

• The GCT usually involves a cladding that consisted of

  2019-04-24

  

  The GCT usually involves a cladding that consisted of reactive bone and fibrosis, with a distinct boundary surrounded by soft tissue. Nevertheless, the active cladding is very thin among patients with severe invasiveness, including tumors that extend directly in into the muscle and fat, or other sig

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